Colib’read on galaxy: a tools suite dedicated to biological information extraction from raw NGS reads

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Colib’read on galaxy: a tools suite dedicated to biological information extraction from raw NGS reads

BACKGROUND With next-generation sequencing (NGS) technologies, the life sciences face a deluge of raw data. Classical analysis processes for such data often begin with an assembly step, needing large amounts of computing resources, and potentially removing or modifying parts of the biological information contained in the data. Our approach proposes to focus directly on biological questions, by ...

متن کامل

Reconstructing viral quasispecies from NGS amplicon reads

This paper addresses the problem of reconstructing viral quasispecies from next-generation sequencing reads obtained from amplicons (i.e., reads generated from predefined amplified overlapping regions). We compare the parsimonious and likelihood models for this problem and propose several novel assembling algorithms. The proposed methods have been validated on simulated error-free HCV and real ...

متن کامل

From raw reads to trees : Whole genome SNP phylogenetics across

1 From raw reads to trees: Whole genome SNP phylogenetics across the tree of 1 life 2 3 Sanaa A. Ahmed, Chien-Chi Lo, Po-E Li, Karen W. Davenport, and Patrick S. G. Chain 4 5 Biome Sciences, Bioscience Division, Los Alamos National Laboratory, MS-M888, Los 6 Alamos, NM 87545 7 Corresponding author: 8 Patrick S.G. Chain 9 Scientist IV 10 Los Alamos National Laboratory 11 MS-M888 12 Los Alamos, N...

متن کامل

Statistical Significance for NGS Reads Similarities

In this work we present a significance curve to segregate random alignments from true matches in by identity sequence comparison, especially suitable for sequencing data produced by NGS-technologies. The experimental approach reproduces the random local ungapped similarities distribution by score and length from which it is possible to asses the statistical significance of any particular ungapp...

متن کامل

Review of Recent Ngs Short Reads Alignment Tools Bmi-231 Final Project, Chenxi Chen Spring 2014

Deciphering the information contained in DNA sequences began decades ago since the time of Sanger sequencing. The development of next generation sequencing makes it possible to study organisms on the genome scale. NGS have been used in various types of studies including genome re-sequencing (DNA-seq), DNA-protein interactions (ChIP-seq), transcriptom reconstruction, quantitative analysis (RNA-s...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: GigaScience

سال: 2016

ISSN: 2047-217X

DOI: 10.1186/s13742-015-0105-2